Dennis J. Bonner, MD

How Suboxone Works

How Suboxone Works

How Suboxone Works

Doctors include Suboxone to treat opioids abuse disorder. The key ingredients naloxone and buprenorphine have a complex and unique action mechanism, including incomplete binding of opioid receptors. These receptors have three significant effects that include;

 ·       Reducing breathing or respiratory depression

·       Decreasing pain 

·       Producing euphoria (feeling of excitement or happiness)

Buprenorphine binds to the receptors in a way that satisfies cravings of heroin and drugs without causing respiratory depression or producing euphoria. 

When buprenorphine binds to the receptors, other drugs like oxycodone or heroin can’t bind with them. The opioid agonist stays longer on the brain receptors (three days approximately). That makes buprenorphine an excellent choice to include in an opioid treatment program.

Naloxone combines with buprenorphine and discourages misuse. As a potent blocker of opioid receptors, it precipitates addicted individuals into opioid withdrawal if they try to convert the dose into an injectable form. Naloxone doesn’t have any side effects if people take it sublingually.